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Beatriz is at her new school; she hopes to have a chance to make friends, and Valentine's Day is the perfect opportunity to do so, but things don't turn out quite as well as they seem.

After a long day of classes, Betty decides it would be a good idea for Nico to study with her; she succeeds, but Nico becomes interested in Patricia, who has a wicked plan to submit a successful science project.

This time, the task is to work in groups to create a proposal for the school TV program; Betty and Nico eventually find other classmates to work with, and although things didn't go quite as expected, the "Ugly Club" learned a new lesson.

It’s the weekend, and Betty goes out with her friends; feeling lonely, Nico decides to get a pet for company. He finds Claudio the chicken and brings him home without permission. Months pass, and then Doña Nicolasa discovers the chicken—the ending is unexpected.

Daniel still wets the bed; Marcela finds out and threatens to reveal his secret at school—though that may not even be necessary, as they are heading off to camp where he could easily be caught. However, Daniel has a plan to prevent that from happening.

The latest trendy toy arrives; Nico wants it, but Doña Nicolasa doesn’t have the money to buy him the toy. However, the creators of "Pokemondongo" purchase a recipe from Nico’s mother, and he ends up getting his new toy.

Betty is the smartest girl in the class; her classmates Marcela and Patricia are envious, so they want to see her fail at something—which is why they convince Hermes to let her enter a beauty pageant, hoping she will lose.

Don Hermes and Julia decide it’s time to explain to Betty how babies come into the world, using a metaphor; meanwhile, at school, she gets stung by a bee, and the drama of becoming a mother begins.

After failing to make the cheerleading squad, the "ugly girls" club is reluctant to help Marce with a bet; however, Betty convinces them, and the girls end up winning a hard-fought soccer match.

It’s time for auditions to play Juliet, and Betty is ready to land the lead role—and get to kiss Armando on a magical night, without Marcela or Patricia standing in the way of love and art.

Betty writes her name next to Armando’s, but the girls from the "squad" notice the diary and want to know who her crush is; however, the diary ends up in Armando’s briefcase, and now it’s time to get it back.

Marcela does not choose Armando for her monitoring campaign, so he decides to help Betty as a way to take revenge for his girlfriend’s disloyalty; and although Betty wants to secure the monitoring role in a fair manner, Armando has a different plan.

Nicolás arrived in class with chickenpox, and Mario—after having touched him—points it out to everyone; now, no one wants to be near him, but Betty helps him, as she has gone through that same situation herself.

It’s a field trip day, and the television station proves to be the perfect place to find fame; the children from the Gimnasio Postmoderno school take part in an audition, and Betty is chosen for the soap opera—but Patricia won’t let that happen.

It’s an emotional day for Nicolás; the Father’s Day musical is approaching, and Nico is determined to find a father figure—at any cost—to introduce to his classmates. The best candidate is Don Hermes.

Following a failed experiment, Professor Gutiérrez is away from the school for a while, and the new substitute teacher has stolen Freddy’s heart—though his feelings are not reciprocated.

Nicolás loves Patricia and intends to win her over by playing soccer—even though he knows it’s not his strong suit—but his luck is set to change with the help of a genie, who provides Nicolás with exactly what he needs to win the heart of his beloved.

A fire causes the school to suffer major losses, and the only person who can save it's Mr. Gutiérrez with his lottery ticket; however, he dreams of traveling to space—yet his love for the school proves greater than the trip itself.

The figure-riding contest is Nicolás’s chance to get a new bicycle; after rigorous training, the day of the competition arrives, and Nicolás emerges as the winner.

The kids head off to school—Betty dressed in her best look—but her classmates mock her, so she asks Nicolás for help; thanks to his chemistry skills, the transformation is striking, though it isn't permanent.

Armando and Mario are going to the stadium, and Freddy doesn’t think twice about joining them; he does everything in his power—going to any length—to get his friends to the stadium so they can watch the Colombian national team play.

Mario the prankster is punished, and in the midst of his punishment, he meets Lulú—the rector’s daughter—who, unbeknownst to him, could become his undoing, as Mario falls in love with another prankster just like himself.

Betty wants to celebrate this special day with her peers, but for her parents, it is very costly to provide everything the little girl needs; nevertheless, Betty manages to have a truly grand First Communion celebration.

Mario Calderón mocks his colleagues for wearing glasses, only for it to be discovered that he needs them too; however, he adamantly refuses to wear them—until an incident occurs that leads him to start using them.

Marcela has declared her eternal love to Armando, but Patrick has arrived from France, and she has become infatuated with him; Armando, feeling jealous, is determined to do whatever it takes to get things back to normal.

Freddy wants to win over Aura María, but he feels she pays him no attention because he has no money; however, that is about to change, as Armando intends to help him.

After a game, the girls in the group realize that Sofia likes Mario; he feels nothing for her, yet she is getting her hopes up—but the person who is actually interested in her is Williamcito.

Mario does not want to take the exam, which leads to him becoming a discipline monitor; he takes his new role very seriously, punishing all his classmates—and even the teacher—but in the end, he learns his lesson.

Nicolás is jealous of Marito Duarte, and during a fit of rage, they are mistaken for one another; Nico ends up dating Patricia, and Marito finally gets a break from the spotlight—though things spiral out of control, everything eventually returns to normal.

Being a snitch is never an option—Nicolás learned that lesson—but what about Armando? A change of group could turn him into the snitch, or perhaps the "chicken," of class 5B.

Dance classes make Sandra feel like she isn’t good at anything, so Betty suggests that basketball might be a good option. Betty is right, but the coach refuses to accept her because she’s a girl—will her trick work?

Armando grows tired of Marcela and her manipulation, creating the perfect opportunity for Betty to win him over; however, Marcela convinces Betty to help her win Armando back instead.

Mario and Armando are the biggest pranksters among the hosts, but it seems Innescita is set to put an end to their bad behavior with a good scare—one that leads to a lesson, a new host, and a new friendship.

Nicolás has a guardian angel, and the angel must teach him how to defend himself—will he succeed? After a few tricks, Nico learns the lesson.

Mario and Armando look for a way to avoid listening and pretend to faint; Gutiérrez notices, and they accidentally damage a trophy. What will they do to avoid being punished?

It’s a new day in the story; the kids bring their pets to the dog show. Nico discovers a dog that plays the piano. He introduce the dog to his classmates, but Baboso doesn’t want to play—though, in the end, they realize that Baboso actually can play.

A chain letter sparks fear at school; Betty doesn’t believe in such things, but a series of events makes her start to doubt—fortunately, she has her dad who helps her put an end to that streak of bad luck.

Betty joins the school band to be close to Armando; Mario notices this and bets that it’s all because of love. Realizing this is the case, they take advantage of the situation to get her to help them with their exams.

The children’s toys keep disappearing—it must be the monster that’s been stalking the students who bring their dolls to school.

This is a chance to win a Nobel Prize, save nature, and gain recognition; Betty and Nico are working on a mega-project, but a misunderstanding puts their friendship at risk.

Nico can’t find anyone to play with, so he decides to create his own friend to have some fun; Verne the robot arrives at school, and after a few mishaps, Nico and Verne learn the true meaning of friendship.

The students go to the circus, discover the mistreatment of the elephants, and set out to fight the villains in order to rescue Elsita and Moscorrofio; they succeed, and the elephants are set free.

Mario and Armando’s pranks no longer have any effect on Gutiérrez; he realizes that Mendoza’s injury is fake, and he intends to show both Mendoza and Calderón that making light of someone’s health is no laughing matter.

It’s movie night, and Nico and Betty decide to watch horror films—after all, they’re big kids now—but it turns out that vampires actually exist, and Nico must avoid getting bitten.

Nicolás has a very bad flu and wants to find out why he isn’t getting better, so he sends the girls to explore inside his body to see why his white blood cells aren’t working—an experience that turns out to be quite an adventure for them.

Mario Calderón has lice from putting on a hat he found in the trash; he realizes it, but says nothing, and instead looks for a way to ensure that all his classmates also become infested with lice.

Freddy doesn’t want to be punished, so he lies to Gutiérrez—and then has to keep lying to avoid being found out—but the situation spirals out of control when the teacher and his classmates come to visit him.

Bertha’s peers tease her about her weight; feeling hurt, she decides to change her lifestyle. Although it’s difficult, she manages to lose weight and takes the lead role in the fashion show away from Patricia—though the diet takes a toll on her health.

Classes are finally coming to an end, and the students at the postmodern school are feeling happy. Mario thinks that nothing could possibly ruin his last day of class—unless Gutiérrez decides to give a math test and Mario gets caught copying from Betty.

Armando is left home alone, as his parents go away on a trip and his grandfather arrives to look after him. It seems this might not be the best vacation after all—or so they think—but an adventure awaits them.

Marcela is tired of being a Valencia, but the discovery of an error leads to her no longer being a Valencia—instead, it is Betty who takes on that surname. Will they adapt to their new lives?

Today is a special day for Armando—it’s his birthday—but no one remembers this all-important date, except for Betty. She wants to give him a very special gift, but Armando treats her poorly.

Betty arrived for her meeting with Armando, but she received an even bigger surprise when she was told she had been awarded a scholarship to France; however, she hesitated because of her love for Armando—but in the end, she decided to go to France.