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As "Pinoy Big Brother: Collab Edition" starts afresh at a new location for its third season, Big Brother opens his doors to 16 housemates, all ready to share their empowering stories and reveal their authentic selves to the world.

The housemates get to know one another as they spend their first night together in the new PBB House. Soon, their teamwork is put to the test as they take on their very first task.

The housemates experience their first morning inside the house and begin getting to know one another. Mikee Quintos is revealed as the second Ka-Collab, joining Robbie in Kuya's secret charity mission.

The housemates continue sharing personal stories connected to special items they brought from home. Their stories reveal more about their families, relationships and personal experiences. Mikee begins recognising Robbie's connection to Kuya's secret mission.

The first weekly task, The Big Foundation, is introduced. Housemates must construct a four-foot tower using wooden blocks and place a miniature PBB house on top. Meanwhile, Mikee and Robbie receive their secret mission to construct the miniature house without being discovered.

Shea celebrates her birthday inside the house. She receives an emotional birthday celebration, including surprise visits from Piolo Pascual, Iñigo Pascual, Darren Espanto, Kyle Echarri, Emilio Daez and River Joseph.

Birthday celebrants Shea and Lans undertake a spooky Halloween challenge. They must transform into a connected pair of aswangs and scare their fellow housemates. Their success determines how much food everyone receives for the Halloween celebration.

The housemates celebrate a joint Halloween party and birthday celebration for Lans and Shea. Meanwhile, Mikee and Robbie complete their secret mission by successfully constructing the miniature PBB house within the 48-hour deadline, earning ₱10,000 for the Big Collab Charity Mission.

The housemates complete their first weekly task by constructing a four-foot tower and keeping it standing for 100 seconds with the miniature PBB house on top. Lans also celebrates her birthday with a surprise message from her father. Relationships and growing romantic interest between Jeo, Shea and Gehlee become a talking point.

Dingdong Dantes and Marian Rivera enter the house for a special activity promoting their upcoming movie Remember. The housemates participate in a memory and character dress-up challenge, recreating characters previously portrayed by the celebrity couple. They also share personal stories about the days they want to remember and forget. Meanwhile, tensions develop between Primo and Calix over friendship, competitiveness and feeling excluded.

Tensions between the male housemates escalate as Calix and Nathan notice changes in Primo's behaviour. Calix feels increasingly excluded as Primo spends more time with Jeo and Anthony. A confrontation follows when Primo discovers that Calix has discussed his concerns with other housemates rather than approaching him directly. Robbie and Jeo attempt to mediate and encourage the two to resolve their misunderstanding.