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After taking a leave of absence from Harvard, Jazz struggles with her mental health and the 100-lb weight gain from her binge eating disorder. With the support of her family, Jazz sets her sights on getting readmitted to school and getting healthy.

Jazz asserts her freedom after her mom crashes the after-party, but when she locks in a date with a new suitor amid a hailstorm of transphobia, her world comes crashing down around her, and there's only one person she wants.

Following Jazz's meltdown, Jeanette outsources help but gets disturbing feedback. Meanwhile, Jazz goes on her first date in four years. Nervous over a kiss, she tries her best to stay out of her head but struggles when a dance lesson goes awry.

Jazz rejects Dayron's kiss, sets a date with an older man, and faces the staggering question of whether she's asexual. Just as soon as Jeanette finds a way to let her daughter go, Jazz's anxiety boils over. Meanwhile, Jaclyn and Tyler meet a trans icon.

Jazz and Yash conclude their first date but land on different pages. Jazz hopes attending a queer speed dating event with Jaclyn will lighten the blow. Meanwhile, Jazz starts to doubt her commitment to Harvard, but telling her parents is another story.

Jazz heads back to Cambridge and comes face-to-face with her newest crush: a woman! Before the sophomore gets too settled, Harvard shares news of a disturbing death threat that complicates a transgender awareness event Jazz is eager to put on.