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In 1889, Nolasco Black, a forensic odontologist, is recruited by the police to assist in the investigation of a murder. "Flammarion", a group of women supports the dentist. A mysterious doctor arrives at the local hospital.

The dentist, wrongly accused, uses his ingenuity to prove his innocence while the real killer plans another crime. With Sofia's help, he uncovers painful truths. The case becomes more complicated when a new victim emerges.

In Veracruz, Nolasco investigates a case of murders involving women, convinced that the killer possesses extensive knowledge of anatomy, but faces resistance from the medical elite.

A death causes chaos at an event. The victim's identity shocks everyone. The prosecutor closes the case despite pressure from the press. The real killer seeks a new victim.

The dentist is poisoned and must find the antidote. Williams plants false clues in his house. This leads the police to believe Nolasco was the killer from the start. Sofía trusts him, and unexpected feelings arise between them.

Nolasco is sent to Ulúa prison, where he is treated like a woman-killer. Williams bribes the prison director to visit the dentist twice. Pardo doubts Nolasco's guilt, but the prosecutor ignores him.

Nolasco is presumed dead in prison. Sofía decides to break into the Englishman's house to find the necessary evidence to arrest him. Williams manages to take the life of someone very close to the dentist.

Six months later, a young boy finds a woman's body in an alley in Mexico City. Nolasco and Sofía, now a couple, along with Urra, try to stop Williams' murders. Later, the couple faces a new mystery in Paris.