Late Show with David Letterman·CBS
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22 seasons · 4261 eps
Season 22
Kristen Wiig, Sen. Elizabeth Warren, The New Pornographers Episode 2
Steve Buscemi, Indy Car Season Champ, Alt-J Episode 3
Tina Fey, Moody McCarthy, Kevin Drew Episode 4
Bill Maher, Henrik Lundqvist, Spoon Episode 5
Michael Strahan, Richard Branson, Interpol Episode 6
Dr. Phil, Katharine McPhee, Death from Above 1979, Ray Benson Episode 7
Jason Bateman, Billy Eichner, Ryan Adams Episode 8
Mindy Kaling, Jake Johannsen, Maddie & Tae Episode 9
Mark Harmon, "Jungle" Jack Hanna Episode 10
Denzel Washington, Lenny Kravitz Episode 11
Kelly Ripa, Jim Gaffigan, Paloma Faith Episode 12
Jerry Seinfeld, Michael Jackson ONE Episode 13
Ted Danson, Andrew Norelli Episode 14
Neil Patrick Harris, Jamie Oliver, Aretha Franklin Episode 15
John Oliver, Maggie Q, Bleachers Episode 16
Bill O'Reilly, Cristin Milioti Episode 17
Johnny Galecki, Andre Benjamin, Delta Spirit Episode 18
Mariska Hargitay, Simon Amstell, Kandace Springs Episode 19
Aziz Ansari, Tom Dreesen Episode 20
Robert Downey Jr., Sarah Paulson, Lizzo Episode 21
Anderson Cooper, Gina Rodriguez, Hatsune Miku Episode 22
Robert Duvall, Elle Fanning, Rival Sons Episode 23
Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley Episode 24
TV host Chelsea Handler; comics Keegan-Michael Key and Jordan Peele; Angaleena Presley performs.
Russell Brand, Dave Grohl, Foo Fighters Episode 25
Michael Keaton, Foo Fighters Episode 26
Bill Murray, Foo Fighters Episode 27
Tom Selleck, Jenny Slate, Foo Fighters Episode 28
Jessica Chastain, Lenny Marcus, Foo Fighters Episode 29
Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis Episode 30
Taylor Swift, Tom Mison Episode 31
Jim Carrey, David Tennant Episode 32
Brian Williams, Perfume Genius Episode 33
Keith Olbermann, Brian Regan, Run the Jewels Episode 34
Martin Short, Father John Misty Episode 35
Jennifer Lopez, Rob Riggle, Kimbra Episode 36
Whoopi Goldberg, Jimmy Page, Mapei Episode 37
Amy Schumer, Jeff Caldwell Episode 38
Katie Holmes, Alex Zanardi Episode 39
Steve Carell, Martha Stewart, OK Go Episode 40
Jennifer Lawrence, Boris Johnson Episode 41
Jon Stewart, Shawn Mendes Episode 42
Kristin Chenoweth; Chris Young Episode 43
Actress Kristin Chenoweth; Chris Young performs.
Jason Sudeikis, Allison Janney, Damien Rice Episode 44
Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger Episode 45
Regis Philbin, Hundred Waters Episode 46
Edward Norton, Jessye Norman Episode 47
Norman Lear, TV on the Radio Episode 48
Seth Rogen, Amy Sedaris Episode 49
Emily Blunt, Adam Resnick, Wu-Tang Clan Episode 50
Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz Episode 51
Joaquin Phoenix, Cristela Alonzo, Al Green Episode 52
Ben Stiller, Olivia Munn, LaLa Brooks Episode 53
Meryl Streep, Rebel Wilson, J. Cole Episode 54
Meryl Streep (Into the Woods (2014)); actress Rebel Wilson (Night at the Museum: Secret of the Tomb (2014)). Also: J. Cole performs, 'Be Free'.
Chris Rock, Sting Episode 55
Jamie Foxx, Robert Klein, Dan Penn Episode 56
Emma Stone Top, Marcus Mariota, Bob Seger Episode 57
New Holiday Toys, Anna Kendrick, Charli XCX Episode 58
Tom Brokaw, Will Nelson & Billy Joe Shaver Episode 59
Rosie O’Donnel,l Jeff Altman Episode 60
Jay Thomas, Josh Brolin, Darlene Love Episode 61
The final Christmas episode. Jay Thomas drops by to once again tell "The best talk show story, ever", then he and David try to knock the meatball off the Christmas tree in the Late Show Quarterback Challenge. An interview with Josh Brolin. The show wraps up with Darlene Love's last Late Show performance of Christmas (Baby Please Come Home).
Kathy Griffin, David Oyelowo, Lera Lynn Episode 62
Ethan Hawke, Allison Williams, Parquet Courts Episode 63
Julianne Moore, Catfish & the Bottlemen Episode 64
Donald Trump, Chelsea Peretti, Foxygen Episode 65
Michael Somerville, Nicole Atkins Episode 66
Jeff Goldblum; comedian Michael Somerville. Also: singer/songwriter Nicole Atkins performs.
Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones Episode 67
Anderson Cooper, Shovels & Rope Episode 68
Amanda Peet, Ryn Weaver Episode 69
Larry David, Dan Patrick, Sleater-Kinney Episode 70
Urban Meyer, Johnny Beehner, Ella Henderson Episode 71
Louis CK, Nicolle Wallace, the Lone Bellow Episode 72
Louis CK|Nicolle Wallace|the Lone Bellow
Andrew Luck, Oscar Isaac, Drenge Episode 73
Viola Davis, Ben Schwartz, Marty Stuart Episode 74
John Oliver, Mayim Bialik, Death Cab for Cutie Episode 75
Aziz Ansari, Brian Kiley, Ben Howard Episode 76
Jack Hanna, Sharon Jones and the Dap-Kings Episode 77
Dr. Phil McGraw, Robin Tunney, Diana Krall Episode 78
Ryan Reynolds, Dierks Bentley Episode 79
Martin Short, Bettye Lavette Episode 80
Sienna Miller, Andy Kindler, Bob Mould Episode 81
Steve Carell, Dr. Cornel West Episode 82
Courtney Love, Chris Elliott, Rhiannon Giddens Episode 83
Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear Episode 84
Tom Hanks, Sturgill Simpson Episode 85
Bill Hader, Pat McGann, Shakey Graves Episode 86
Matthew Perry, Adam Scott, Kishi Bashi Episode 87
Dakota Johnson, David Tochinskiy, Twin Shadow Episode 88
Will Smith, Grizfolk Episode 89
Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko Episode 90
Kid Scientists, Sean Hayes, Judah & the Lion Episode 91
Helen Mirren, the 2015 Daytona 500 winner, Steve Earle Episode 92
Matthew Broderick, Ellie Kemper, JD McPherson Episode 93
Julianna Margulies, Eric Ripert, Glass Animals Episode 94
Kevin Spacey, Lily James, Alabama Shakes Episode 95
Patricia Arquette, Will Butler Episode 96
Kelsey Grammer, Stevie Wonder Episode 97
Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew Episode 98
Kevin Bacon, Jimmie Walker, Airborne Toxic Event Episode 99
Shailene Woodley, Dr. Cornel West, Matthew E. White Episode 100
Will Ferrell, Glen Hansard Episode 101
Norm MacDonald, Theo James Episode 102
Ben Stiller, Tove Lo Episode 103
Bill O'Reilly, Aubrey Plaza Episode 104
James Franco, Jake Johannsen, Action Bronson Episode 105
Neil Patrick Harris, Charlie Cox, the Suffers Episode 106
David Duchovny, Josh Gad, Houndmouth Episode 107
Sen. Al Franken, Billy Eichner, David Sanborn Episode 108
Kelly Ripa, Aasif Mandvi, Fat White Family Episode 109
Mike Myers, Nick Griffin, Banks Episode 110
Sarah Jessica Parker, Julie Chen, Asleep at the Wheel Episode 111
Billy Crystal, Chris Russo, Chris Stapleton Episode 112
Michael J. Fox, Iron & Wine, Ben Bridwell Episode 113
Kevin James, Tom Dreesen, Tracy Chapman Episode 114
Alec Baldwin, John Mayer Episode 115
John Travolta, Amy Schumer, the Waterboys Episode 116
Piedmont Bird Callers, Paul Rudd Episode 117
Bruce Willis, Dawes Episode 118
Robert Downey Jr., Chris Russo, Elvis Costello Episode 119
Jerry Seinfeld, Jason Isbell & Amanda Shires Episode 120
Scarlett Johansson, John Mellencamp, Todd Rundgren Episode 121
Michael Keaton, Future Islands Episode 122
Jack Hanna, John Popper Episode 123
First Lady Michelle Obama Hootie and the Blowfish Episode 124
Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor Episode 125
President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile Episode 126
Reese Witherspoon, Nathan Lane, Mumford & Sons Episode 127
Martin Short, Norah Jones Episode 128
Tina Fey, First Aid Kit Episode 129
Ray Romano, Brian Regan, Dave Matthews Band Episode 130
Howard Stern, Don Rickles Episode 131
Bill Clinton, Adam Sandler Episode 132
Julia Roberts, Paul Shaffer, Ryan Adams Episode 133
Al Pacino, George Clooney, Tom Waits Episode 134
Oprah Winfrey, Norm Macdonald Episode 135
Tom Hanks, Eddie Vedder Episode 136
Bill Murray, Bob Dylan Episode 137
The Final Late Show with David Letterman Episode 138
6,028th broadcast
Episode 149 Episode 149
The final episode includes surprises, memorable highlights and the last Top Ten List.
139 episodes in Season 22
Some details come from TheTVDB.