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Fulfilling her father's wish, a young Cleopatra ascends the throne in Egypt amid sibling rivalries and forms an alliance with a noted Roman leader.

The birth of a child unites Rome and Egypt, putting Cleopatra in a favorable position until a shocking murder puts her and her son's lives under threat.

Cleopatra forges a strategic relationship for personal gains as Egypt thrives under her rule. Later, she makes a bold decision in the heat of battle.

While Octavian and the Roman army target Egypt, crises erupt on and off the battlefield. Can Cleopatra protect herself, her children and her empire?