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The game is on. Ten strangers meet to take part in 'La Jugada de Machiavelli' (Machiavelli's Move). Lies are not long in coming, and one contestant puts a target on their back in exchange for help saving themself from expulsion. As the players prepare for their first mission at a luxury auction, saboteurs from the shadows disrupt their entire strategy. A final twist of events proves that there is more than one enemy in the group.

One player has already been eliminated, and those who have survived are seeing their fortunes dwindle as other players are secretly receiving messages and making deals with Machiavelli and the saboteurs. The contestants face a new mission. They must find the antidote to a deadly virus in a hospital where not everyone will make it out alive. Someone will be left behind. Maybe they should start running.

A contestant finds themself in a tight spot at the hospital, but time is running out and the players need to earn as much money as possible from the mission if they don't want the prize fund to dwindle to nothing. Machiavelli has prepared a special treat for those who have made it through the elimination round. This time, the whole group takes the offer of immunity, but they have to trade a clue for it.

The immunity box jeopardises the third mission to the thermal plant. However, the factory is not the only thing at risk; the contestants' morale is as well. The previous elimination has left them feeling shaken, and they must prepare for the most challenging mission yet. Have you noticed anyone who seems more nervous than the others? Perhaps it's because the saboteurs see their power, and above all their survival, at risk.

A contestant leaves ‘La Jugada de Maquiavel’ (Machiavelli's Move.) Will it be a player or a saboteur? The fourth mission takes place in the mansion itself, but the contestants are confused and must face an unexpected dilemma. They are about to make the hardest decision they have ever had to make as a group. As night falls, they must search for the ammunition boxes in the woods before it's too late and everything goes up in smoke.

When the finalists arrive at the hangar to prepare for their final mission, they discover a big surprise and are finally able to confess. Who are the saboteurs? The final challenge begins: a sabotage-filled course to reach Machiavelli's archive, retrieve the mask, and claim the prize. Trusting the wrong person could mean the difference between winning and losing.