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After a botched amputation, surgeon Robert is put under pressure by the royal physician.

Caroline bags an invitation to meet her hero, Charles Dickens.

William concocts a daring plan to cure a deluded patient.

Caroline arranges to meet a charismatic hypnotist for a demonstration of his powers.

The Bishop needs his appendix removed, but he won’t agree to pain relief or surgery.

Raucous medical comedy set in Victorian London about four pioneers, friends and rivals - fighting to make a mark on the world and save lives.